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Computerized cognitive training and functional recovery in major depressive disorder: A meta-analysis
Jeffrey N Motter1, Monique A Pimontel1, David Rindskopf2
1The Graduate Center, City University of New York, USA; Queens College, City University of New York, USA.
Journal of Affective Disorders
|October 6, 2015
Summary
Computerized cognitive training (CCT) shows promise for improving depression symptoms and daily functioning. However, its effects on specific cognitive functions like attention and memory remain inconsistent, warranting further research.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Depression frequently presents with cognitive and functional impairments.
- Antidepressant treatments are not always effective for all individuals.
- Computerized cognitive training (CCT) is an emerging intervention for cognitive deficits.
Purpose of the Study:
- To systematically review and meta-analyze randomized controlled trials on CCT efficacy in depressive disorders.
- To determine the impact of CCT on mood, cognition, and daily functioning in adults with depression.
Main Methods:
- Systematic literature search of PsycINFO and MEDLINE for high-quality randomized controlled trials.
- Inclusion of 9 trials involving depressed adults.
- Application of a 3-level Bayesian hierarchical linear model to estimate effect sizes for mood, cognition, and functioning.
Main Results:
- Significant small-to-moderate effects observed for symptom severity and daily functioning.
- Moderate-to-large effects found for attention, working memory, and global functioning.
- No significant effects on executive functioning or verbal memory; CCT efficacy decreased with age.
Conclusions:
- CCT demonstrates potential for improving depressive symptoms and everyday functioning.
- Cognitive benefits of CCT are inconsistent across different domains.
- Limitations include small sample sizes, short intervention durations, and high heterogeneity in some measures.
