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An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
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[Metastatic urinary bladder involvement in breast cancer]
Ana Avargues1, Saturnino Luján1, Laura Palomar1
1Service of Urology. Hospital Universitari i Politècnic La Fe. Valencia. Spain.
Archivos Espanoles De Urologia
|October 6, 2015
Summary
Metastasis of primary breast cancer to the urinary bladder is rare. Urinary symptoms in breast cancer patients warrant investigation for bladder metastases, even with widespread disease.
Area of Science:
- Oncology
- Urology
- Pathology
Background:
- Primary breast carcinoma is a common malignancy.
- Metastasis typically occurs to distant organs like bone, lung, liver, and brain.
- Urinary bladder metastasis from breast cancer is exceptionally rare.
Observation:
- Three cases of invasive lobular breast carcinoma with urinary bladder metastasis are presented.
- Patients' ages ranged from 49 to 52 years.
- Two patients presented with hematuria; one was diagnosed incidentally via CT scan.
Findings:
- All three patients had advanced breast cancer with metastases to other sites at the time of bladder metastasis diagnosis.
- Treatment was palliative, and deaths were attributed to other comorbidities.
- Invasive lobular carcinoma histology was confirmed in all cases.
Implications:
- The occurrence of bladder metastases from breast cancer, though infrequent, should be considered in the differential diagnosis.
- Urinary tract symptoms in patients with a history of breast cancer necessitate thorough diagnostic evaluation to exclude metastatic disease.
- Early detection and management strategies for rare metastatic patterns require further investigation.
