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Related Experiment Video

Updated: Apr 1, 2026

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Fully Integrated Biopotential Acquisition Analog Front-End IC.

Haryong Song1, Yunjong Park2, Hyungseup Kim3

  • 1Department of Electronics, Chungnam National University, Daejeon, 305-764, Korea. zealshr@cnu.ac.kr.

Sensors (Basel, Switzerland)
|October 6, 2015
PubMed
Summary
This summary is machine-generated.

This study presents a novel biopotential acquisition analog front-end integrated circuit. It achieves low noise and high common-mode rejection, improving signal quality for biopotential measurements.

Keywords:
DC servo loop (DSL)biopotentialcapacitive input boosting loop (CIBL)capacitively-coupled chopper instrumentation amplifier (CCIA)ripple reduction loop (RRL)

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Area of Science:

  • Electrical Engineering
  • Biomedical Engineering
  • Integrated Circuit Design

Background:

  • Biopotential signal acquisition requires low-noise, high-precision analog front-ends (AFEs).
  • Existing AFEs face challenges with DC offset, low-frequency artifacts, and common-mode rejection, especially with electrode mismatch.
  • Minimizing input-referred noise (IRN) and maximizing common-mode rejection ratio (CMRR) are critical for accurate biopotential monitoring.

Purpose of the Study:

  • To present a novel biopotential acquisition analog front-end (AFE) integrated circuit (IC).
  • To achieve low input-referred noise (IRN) and high common-mode rejection ratio (CMRR) using innovative compensation loops.
  • To demonstrate the AFE's effectiveness in biopotential signal acquisition under challenging conditions.

Main Methods:

  • Design and fabrication of a two-stage capacitively coupled chopper instrumentation amplifier (CCIA) based AFE.
  • Integration of three compensation loops: DC servo loop (DSL), ripple rejection loop (RRL), and capacitive impedance boosting loop (CIBL).
  • Fabrication using a 0.18 μm CMOS process and integration of a fourth-order band-pass filter (BPF).

Main Results:

  • The fabricated AFE IC achieved a low IRN of 0.94 μVRMS in the 1 Hz to 100 Hz pass-band.
  • The maximum amplifying gain reached 71.9 dB.
  • The CIBL effectively enhanced CMRR from 57.9 dB to 67 dB at 60 Hz, even with electrode mismatch.

Conclusions:

  • The presented biopotential AFE IC effectively addresses key challenges in biopotential signal acquisition.
  • The integrated compensation loops (DSL, RRL, CIBL) significantly improve noise performance and CMRR.
  • This AFE IC is suitable for high-quality biopotential monitoring applications, offering reconfigurable gain and bandwidth.