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Shrinking the Supply Chain for Implantable Coronary Stent Devices
Sean S Moore1, Kevin J O'Sullivan2, Francesco Verdecchia3
1Department of Design & Manufacturing Technology, University of Limerick, Limerick, Republic of Ireland. sean.moore@ul.ie.
Annals of Biomedical Engineering
|October 7, 2015
Summary
Future stenting could involve custom, patient-specific devices made in minutes. This revolution in stent design and manufacturing aims to improve patient care through rapid, on-demand fabrication and deployment.
Area of Science:
- Biomedical Engineering
- Materials Science
- Medical Device Manufacturing
Background:
- Stenting is crucial for managing various diseases across cardiovascular, biliary, and urogenital systems.
- Significant technical advancements have been made in stent technology, moving from metallic to bio-absorbable materials.
Purpose of the Study:
- To explore the potential of advanced manufacturing techniques to revolutionize stent design, production, and supply chains.
- To propose a future model for highly condensed stent supply chains, enabling rapid, customized stent generation.
Main Methods:
- Review of current stenting trends and technological advancements.
- Conceptualization of a future integrated system for on-demand stent design, manufacturing, and deployment.
- Outline of the Generating Eluting Stents In Situ (GENESIS) program and preliminary experimental findings.
Main Results:
- Current stent supply chains (~150 days) can potentially be reduced to approximately 20 minutes.
- Cardiologists could become designers and manufacturers, providing custom stents for individual patient needs.
- Early experimental work on the GENESIS program shows promise for in-situ stent generation.
Conclusions:
- Additive manufacturing and bio-absorbable materials offer a paradigm shift in stent technology.
- The proposed model enables personalized medicine by delivering patient-specific stents rapidly.
- Overcoming technical challenges is crucial for realizing the full potential of in-situ stent generation and deployment.
