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Falls and Depression in Men: A Population-Based Study.

Amanda L Stuart1, Julie A Pasco1,2, Felice N Jacka1,2,3,4

  • 11 IMPACT Strategic Research Centre, Deakin University, Geelong, Victoria, Australia.

American Journal of Men'S Health
|October 7, 2015
PubMed
Summary
This summary is machine-generated.

Men with current major depressive disorder (MDD) are over twice as likely to fall. This increased fall risk in depressed men was not explained by age or medication, highlighting a need for further investigation.

Keywords:
SCID-1/NPdepressionfallsosteoporosispsychotropic medication

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Area of Science:

  • Gerontology
  • Psychiatry
  • Epidemiology

Background:

  • The association between falls and depression is well-documented in elderly populations.
  • However, research on this link in younger adults, especially men, remains limited.

Purpose of the Study:

  • To investigate the relationship between major depressive disorder (MDD) and falls in a population-based sample of adult men.
  • To explore factors that may mediate or confound this association.

Main Methods:

  • A population-based sample of 952 men (aged 24-97 years) from the Geelong Osteoporosis Study was assessed.
  • Major depressive disorder (MDD) was diagnosed using the Structured Clinical Interview for DSM-IV-TR.
  • Data on falls, gait, body mass index, smoking, alcohol, and psychotropic medication use were collected over a 5-year follow-up.

Main Results:

  • 3.6% of men had 12-month MDD, and 18.4% reported at least one fall in the past year.
  • Men with 12-month MDD had more than double the odds of falling (age-adjusted OR: 2.22, 95% CI [1.03, 4.80]).
  • This association remained significant after adjusting for age, psychotropic medication use, gait, BMI, smoking, and alcohol intake.

Conclusions:

  • Current major depressive disorder is significantly associated with an increased likelihood of falls in men.
  • The observed link between MDD and falls is not explained by age or psychotropic medication use.
  • Further research is warranted to understand the mechanisms underlying this increased fall risk in depressed men.