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Growth and development after oesophageal atresia surgery: Need for long-term multidisciplinary follow-up
Hanneke IJsselstijn1, Saskia J Gischler1, Leontien Toussaint1
1Department of Intensive Care and Paediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.
Insights
Long-term survival for oesophageal atresia patients exceeds 90%. However, growth and neurodevelopmental issues are common, necessitating multidisciplinary adult care to enhance quality of life.
Area of Science:
- Pediatric Surgery
- Developmental Pediatrics
- Longitudinal Health Outcomes
Background:
- Oesophageal atresia (OA) survival rates now exceed 90%.
- Long-term follow-up has evolved from surgical/gastrointestinal focus to a multidisciplinary approach.
- Focus is shifting to long-term morbidity, particularly growth and neurodevelopment.
Purpose of the Study:
- To review the literature on long-term morbidity in oesophageal atresia patients.
- To discuss physical growth and neurodevelopmental outcomes.
- To propose a multidisciplinary follow-up schedule into adulthood.
Main Methods:
- Literature review of long-term morbidity in oesophageal atresia patients.
- Analysis of studies focusing on physical growth (stunting, wasting).
- Review of neurodevelopmental outcomes beyond preschool age.
Main Results:
- Growth problems like stunting and wasting are frequent in OA patients.
- Sufficient longitudinal data on catch-up growth into adulthood is lacking.
- OA patients are at risk for academic and motor function delays, with limited data beyond preschool age.
Conclusions:
- Growth retardation determinants in OA patients require further investigation.
- Long-term neurodevelopmental studies are scarce but indicate potential academic and motor issues.
- A multidisciplinary follow-up into adulthood is crucial for improving OA patient quality of life.
Abstract:
Survival rates in oesophageal atresia patients have reached over 90%. In long-term follow-up studies the focus has shifted from purely surgical or gastrointestinal evaluation to a multidisciplinary approach. We reviewed the literature on the long-term morbidity of these patients and discuss mainly issues of physical growth and neurodevelopment. We conclude that growth problems - both stunting and wasting - are frequently seen, but that sufficient longitudinal data are lacking. Therefore, it is unclear whether catch-up growth into adolescence and adulthood occurs. Data on determinants of growth retardation are also lacking in current literature. Studies on neurodevelopment beyond preschool age are scarce but oesophageal atresia patients seem at risk for academic problems and motor function delay. Many factors contribute to the susceptibility to growth and development problems and we propose a multidisciplinary follow-up schedule into adulthood future care which may help improve quality of life.
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