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Related Concept Videos

Blood Flow01:29

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Blood Types02:20

Blood Types

Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Studies I: ABG and VBG01:26

Blood Studies I: ABG and VBG

Blood studies are critical in the medical field, enabling healthcare professionals to assess a patient's health status accurately. This page will focus on two significant blood studies: Arterial Blood Gas (ABG) and Venous Blood Gas (VBG).
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to reabsorb or...

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Related Experiment Video

Updated: Jun 29, 2026

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture
05:27

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture

Published on: August 23, 2007

Looking for blood.

Pauline Formaglio1, Rogerio Amino2

  • 1Institute of Molecular and Clinical Immunology, Otto-von-Guericke University, Magdeburg, Germany.

Elife
|October 7, 2015
PubMed
Summary
This summary is machine-generated.

New in vivo imaging shows how malaria parasites invade the bloodstream. This research offers fresh insights into malaria parasite entry mechanisms for future therapeutic targets.

Keywords:
Plasmodiumgliding motilityinfectious diseasemalariamicrobiologymouseskinsporozoite

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Sequential Blood Collection from Inferior Vena Cava Followed by Portal Vein to Evaluate Gut Microbial Metabolites in Mice

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Last Updated: Jun 29, 2026

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture
05:27

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture

Published on: August 23, 2007

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

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Sequential Blood Collection from Inferior Vena Cava Followed by Portal Vein to Evaluate Gut Microbial Metabolites in Mice

Published on: June 21, 2024

Area of Science:

  • * Infectious Diseases
  • * Parasitology
  • * Medical Imaging

Background:

  • * Malaria remains a significant global health burden, caused by Plasmodium parasites.
  • * Understanding parasite invasion pathways is crucial for developing effective interventions.
  • * Previous studies relied on in vitro methods, limiting real-time observation of invasion dynamics.

Purpose of the Study:

  • * To visualize and analyze the in vivo process of malaria parasite invasion into red blood cells.
  • * To identify key molecular and cellular events during the in vivo invasion.
  • * To provide a foundation for novel anti-malarial drug development targeting invasion.

Main Methods:

  • * Utilized advanced in vivo imaging techniques to observe malaria parasite-host interactions in a live organism.
  • * Employed fluorescently labeled parasites and high-resolution microscopy for detailed visualization.
  • * Analyzed dynamic video recordings to track parasite movement and cellular changes during invasion.

Main Results:

  • * In vivo imaging revealed previously unobserved steps in the malaria parasite's entry into the bloodstream.
  • * Detailed the spatiotemporal dynamics of parasite attachment, invasion, and red blood cell remodeling.
  • * Identified specific host cell receptors and parasite ligands involved in the invasion process.

Conclusions:

  • * In vivo imaging provides unprecedented insights into malaria parasite invasion biology.
  • * The findings highlight critical targets for future anti-malarial strategies.
  • * This research advances our understanding of Plasmodium pathogenesis and host-parasite interactions.