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The Washington University Central Neuroimaging Data Archive.

Jenny Gurney1, Timothy Olsen2, John Flavin1

  • 1Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

Neuroimage
|October 7, 2015
PubMed
Summary

The Central Neuroimaging Data Archive (CNDA) at Washington University supports over 1000 studies, offering diverse neuroimaging data, including MR and PET scans. A portion of this valuable research data is accessible to external scientists upon request.

Keywords:
Alzheimer's diseaseAnonymizationArchiveBrain metabolismCNDACancerCentral Neuroimaging Data ArchiveControlsDataDatabaseDe-identifyHIVImagingInformaticsJAATMulti-centerMulti-siteNeuroinformaticsPipelineSharingSickle-cell anemiaTourette syndromeWashington UniversityXNAT

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Area of Science:

  • Neuroimaging Informatics
  • Biomedical Data Archiving

Background:

  • The Central Neuroimaging Data Archive (CNDA) at Washington University has facilitated neuroimaging research since the early 2000s.
  • CNDA is built on XNAT, an open-source platform that originated from CNDA's codebase.
  • It archives data from over 1000 studies, involving 36,000 subjects and 60,000 imaging sessions.

Purpose of the Study:

  • To provide an overview of the CNDA's capabilities and data holdings.
  • To highlight the accessibility of CNDA data for external research collaborations.

Main Methods:

  • The CNDA utilizes an XNAT-based imaging informatics system.
  • It hosts a wide array of imaging modalities, predominantly Magnetic Resonance (MR) and Positron Emission Tomography (PET) of the human brain.
  • Data includes imaging sessions, and in some cases, associated clinical, psychometric, tissue, or genetic information.

Main Results:

  • CNDA supports a vast repository of neuroimaging data from diverse research studies.
  • The archive includes various imaging modalities, with a focus on brain MR and PET.
  • Approximately 20% of CNDA's data is available to external researchers by request.

Conclusions:

  • The CNDA serves as a critical resource for neuroimaging research, offering extensive data from numerous studies.
  • Its data, particularly brain MR and PET, supports research in areas like Alzheimer's disease, metabolism, cancer, HIV, sickle cell anemia, and Tourette syndrome.
  • The availability of CNDA data to external researchers fosters broader scientific collaboration and discovery.