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Synchronous Ipsilateral Parotid Tumors with Cytologic-Histologic Correlation.
Kristina Gvozdjan1, John V Groth1, Tushar N Patel1
1Department of Pathology, University of Illinois Hospital & Health Sciences System, 840 S. Wood St., 130 CSN, Chicago, IL, 60612, USA.
Head and Neck Pathology
|October 7, 2015
Summary
This case report details a rare instance of simultaneous Warthin tumor and basal cell adenoma in a patient's parotid gland. It highlights the importance of accurate cytologic-histologic correlation for diagnosing synchronous salivary gland tumors.
Area of Science:
- Head and Neck Pathology
- Salivary Gland Neoplasms
- Oncology
Background:
- Synchronous tumors in major salivary glands are exceptionally rare.
- This study focuses on a unique case of concurrent Warthin tumor and basal cell adenoma in the parotid gland.
Observation:
- A 54-year-old female smoker presented with a growing left parotid mass.
- Imaging revealed a superficial solid mass adjacent to a deep cystic mass.
- Fine needle aspiration showed mixed cell types, including oncocytic and basaloid cells.
Findings:
- Surgical resection confirmed two distinct adjacent masses: a Warthin tumor and a basal cell adenoma (membranous type).
- The Warthin tumor exhibited oncocytic cells and lymphoid stroma.
- The basal cell adenoma presented as cystic with basaloid cell nests and basement membrane material.
Implications:
- This is the first reported case of synchronous Warthin tumor and basal cell adenoma in the parotid gland with detailed cytologic-histologic correlation.
- Accurate diagnosis of multiple salivary gland tumors is crucial for appropriate management.
- This case expands the understanding of rare salivary gland tumor co-occurrences.

