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Related Concept Videos

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
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Regional Terms01:12

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Regional terms describe anatomy by dividing the body parts into different regions that contain structures involved in contributing similar functions. Using these terms helps increase the accurate description and identification of the particular region of interest or region affected by the disease.
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Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

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Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
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Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

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Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
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Local Anesthetics: Pharmacokinetics01:13

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The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
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Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

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Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
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Hand: Clinical Anatomy and Regional Approaches with Injectable Fillers.

Marc Lefebvre-Vilardebo1, Patrick Trevidic, Amir Moradi

  • 1Carnac and Paris, France; Vista, Calif.; Coconut Grove, Fla.; and San Antonio, Tex. From E2e; private practice; Aesthetic Dermatology, Division of Dermatology and Cutaneous Surgery, University of Texas Health Sciences Center at San Antonio; and Bucay Center for Dermatology and Aesthetics.

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Summary
This summary is machine-generated.

Cosmetic physicians can now safely rejuvenate hands. A new Scrape Skin Threading Technique precisely places fillers in the optimal fascial plane on the hand

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Area of Science:

  • Anatomy
  • Cosmetic Surgery
  • Dermatology

Background:

  • Increasing demand for hand rejuvenation procedures.
  • Current techniques often adapted from facial rejuvenation.
  • Need for anatomical understanding of the hand dorsum for safe filler injection.

Purpose of the Study:

  • To conduct an anatomical study of the hand dorsum.
  • To identify the optimal location for injectable filler deposition.
  • To design a safe and effective filler injection technique for hand rejuvenation.

Main Methods:

  • Anatomical dissections of 19 fresh cadaveric hands.
  • Duplex ultrasound investigation of 28 healthy hands.
  • Development and testing of the Scrape Skin Threading Technique (SSTT) on cadavers using MRI and dissection, compared to other methods.

Main Results:

  • The fascial plane between dermis and tendons measures 0.3–2.2 mm, featuring a 3D sponge-like structure with veins throughout.
  • No pre-defined safe space was identified; the undersurface of the dermis is the optimal filler deposition site.
  • The SSTT was the only technique ensuring precise filler placement within the fascial layer.

Conclusions:

  • The Scrape Skin Threading Technique (SSTT) allows safe and accurate injection of fillers.
  • The undersurface of the dermis is the anatomically ideal location for hand dorsum filler enhancement.
  • SSTT provides optimal filler placement for improved hand appearance.