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Published on: December 22, 2020
Aesthetic Uses of Neuromodulators: Current Uses and Future Directions
Michael S Gart1, Karol A Gutowski
1Chicago, Ill. From the Department of Surgery, Division of Plastic and Reconstructive Surgery, Northwestern Memorial Hospital; and Division of Plastic Surgery, University of Illinois.
Background:
The introduction of neuromodulators for aesthetic facial improvements greatly expanded the limits of nonsurgical facial rejuvenation. Although many current uses are considered "off-label," the widespread acceptance and favorable safety profile of properly used botulinum toxins have made them one of the most common aesthetic treatments available.
Methods:
A literature review of current facial aesthetic uses of various botulinum toxin preparations was done, and general concepts were identified.
Results:
Currently, Food and Drug Administration-approved botulinum toxin preparations onabotulinumtoxinA (Botox), abobotulinumtoxinA (Dysport), and incobotulinumtoxinA (Xeomin) have similar off-label indications and clinical uses.
Conclusions:
Although not considered interchangeable, administration and clinical outcomes are not much different between the 3 commonly used botulinum products. The impact of botulinum products currently in development has yet to be determined.
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