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Changing presentation of cutaneous malignant melanoma
Anders Klit1, Cecilie Brandt Lassen, Caroline Holkmann Olsen
1akli@regionsjaelland.dk.
Danish Medical Journal
|October 7, 2015
Summary
Cutaneous malignant melanoma is rising in Denmark. This study found melanoma affects more females, who are younger, with changing anatomical distribution and decreasing tumor thickness over time.
Area of Science:
- Dermatology
- Oncology
- Epidemiology
Background:
- Rising incidence of cutaneous malignant melanoma in Denmark and Europe.
- Need to investigate current patient and tumor characteristics.
Purpose of the Study:
- Investigate patient and tumor characteristics of cutaneous malignant melanoma.
- Analyze current trends in melanoma diagnosis and presentation.
Main Methods:
- Cross-sectional study utilizing data from the Danish Melanoma Register.
- Inclusion of all patients diagnosed with cutaneous malignant melanoma in Healthcare Region Zealand (2012-2013).
Main Results:
- 520 patients with invasive cutaneous malignant melanoma identified.
- Females more frequently affected, younger than males, with varied anatomical distribution.
- Sentinel lymph node biopsy outcome correlated with tumor thickness.
Conclusions:
- Trend towards increased age at diagnosis for cutaneous malignant melanoma.
- Decreasing tumor thickness and evolving topical distribution in females towards a male pattern.
- Comparison with earlier Danish studies reveals significant shifts in melanoma characteristics.
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