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Gut Microbiota Interacts With Brain Microstructure and Function

José-Manuel Fernandez-Real1, Matteo Serino1, Gerard Blasco1

  • 1Department of Diabetes, Endocrinology and Nutrition (J.-M.F.-R., W.R.), Institut d'Investigació Biomédica de Girona, CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBERobn, CB06/03/0010) and Instituto de Salud Carlos III, Girona, 17007 Spain; Institut National de la Santé et de la Recherche Médicale (M.S., R.B.), Toulouse, France; Unité Mixte de Recherche 1048 (M.S., R.B.), Institut de Maladies Métaboliques et Cardiovasculaires, Université Paul Sabatier, F-31432 Toulouse Cedex 4, France; Girona Biomedical Research Institute, Department of Radiology-Institut de Diagnostic per la Imatge (G.B., J.P.), Hospital Universitari Dr Josep Trueta, Girona, 17007 Spain; Department of Computer Science, Applied Mathematics, and Statistics (J.D.-E.), University of Girona, Girona, 17071 Spain; Department of Psychiatry (F.F.-A.), University Hospital of Bellvitge-IDIBELL, Barcelona, CIBERobn, Instituto Salud Carlos III, Barcelona, 08908 Spain; and Nutren Group, Department of Experimental Medicine (M.P.-O.), PCiTAL-IRBLleida-Universitat de Lleida, Lleida, 25198 Spain.

The Journal of Clinical Endocrinology and Metabolism
|October 8, 2015
PubMed
Summary

Obesity alters the gut microbiome, impacting brain structure and cognitive function. Increased gut bacterial diversity is linked to better brain health and cognitive performance in humans.

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