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Fibromyalgia: A Critical and Comprehensive Review.

Andrea T Borchers1, M Eric Gershwin2

  • 1Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, 451 Health Sciences Drive, Suite 6510, Davis, CA, 95616, USA.

Clinical Reviews in Allergy & Immunology
|October 9, 2015
PubMed
Summary
This summary is machine-generated.

Fibromyalgia, a complex functional somatic syndrome, presents with widespread pain, fatigue, and sleep issues. Effective management focuses on education, physical therapy, exercise, and approved medications, avoiding opioids.

Keywords:
Chronic fatigue syndromeChronic painCopingFibromyalgiaOpiatesPatient supportStressTrauma

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Area of Science:

  • Medical Science
  • Rheumatology
  • Psychiatry

Background:

  • Fibromyalgia is a poorly classified functional somatic syndrome.
  • It shares symptoms like myalgias, arthralgias, fatigue, and sleep disturbances with other somatization disorders.
  • Despite theories, limited evidence links fibromyalgia to inflammatory, infectious, or autoimmune conditions.

Purpose of the Study:

  • To provide an overview of fibromyalgia as a functional somatic syndrome.
  • To emphasize the importance of recognizing and seriously treating fibromyalgia patients.
  • To discuss current understanding of its etiology and recommended treatment approaches.

Main Methods:

  • Literature review and synthesis of existing research on fibromyalgia.
  • Analysis of diagnostic overlaps with other somatization disorders.
  • Evaluation of proposed etiological factors and treatment strategies.

Main Results:

  • Fibromyalgia is characterized by significant overlap with other functional somatic syndromes.
  • There is a lack of strong evidence supporting inflammatory, infectious, or autoimmune causes.
  • Physical trauma is not demonstrably linked to fibromyalgia development or exacerbation.

Conclusions:

  • Fibromyalgia requires serious medical attention and optimal patient care.
  • Treatment should prioritize education, physical therapy, nutrition, exercise, and approved pharmacotherapy.
  • Opioid use and polypharmacy should be avoided; positive outlook and support are crucial for management.