Related Experiment Video
Updated: Apr 1, 2026
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
Transplantation of Tissue-Engineered Cartilage in an Animal Model (Xenograft and Autograft): Construct Validation
Hitoshi Nemoto1,2, Deborah Watson1, Koichi Masuda3
1Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, School of Medicine, University of California, La Jolla, San Diego, CA, USA.
Abstract:
Tissue engineering holds great promise for cartilage repair with minimal donor-site morbidity. The in vivo maturation of a tissue-engineered construct can be tested in the subcutaneous tissues of the same species for autografts or of immunocompromised animals for allografts or xenografts. This section describes detailed protocols for the surgical transplantation of a tissue-engineered construct into an animal model to assess construct validity.
