Related Experiment Video
Updated: Apr 1, 2026
08:50
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
16.9K
Erectile dysfunction as a predictor of advanced vascular age.
D Djordjevic1, I Vukovic1, D Milenkovic Petronic1
1Clinic of Urology, Clinical Centre of Serbia, Belgrade, Serbia.
Andrology
|October 9, 2015
Summary
Erectile dysfunction (ED) is a significant marker for advanced vascular age (VA), indicating atherosclerosis. Early screening for ED can help identify individuals benefiting from lifestyle changes and treatments to manage cardiovascular risk.
Area of Science:
- Cardiology
- Urology
- Vascular Health
Background:
- Vascular age (VA) reflects atherosclerotic burden, differing from chronological age (CA).
- Erectile dysfunction (ED) is recognized as an early indicator of atherosclerosis.
- A discrepancy between VA and CA may signify heightened cardiovascular risk.
Purpose of the Study:
- To investigate the predictive capability of ED in assessing the gap between VA and CA.
- To determine if ED is an independent predictor of advanced VA.
Main Methods:
- Cross-sectional study involving men from urology and cardiology outpatient clinics.
- Participants were categorized into five groups based on ED, hypertension, type 2 diabetes, and coronary artery disease history.
- Hierarchical multiple regression analysis was employed to assess ED's predictive value for advanced VA.
Main Results:
- Vascular age predominance over chronological age was significantly higher in men with coexisting ED and hypertension compared to other groups.
- Erectile dysfunction was identified as a highly significant marker (p < 0.01) of advanced VA.
- ED independently explained 6.1% of the variance in the VA-CA discrepancy.
Conclusions:
- ED assessment can contribute to a more comprehensive prediction of advanced vascular age.
- Screening for ED in at-risk populations may identify individuals who would benefit from early interventions.
- Incorporating ED evaluation into cardiovascular risk assessment could improve patient management strategies.
Related Concept Videos
01:20Disorders of the Male Reproductive System
5.4K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.4K
01:30Peripheral Artery Disease I: Introduction
629
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
629
01:30Coronary Artery Disease I: Introduction
1.6K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.6K
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
681
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
681
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
764
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
764
01:17Ischemic Heart Disease: Overview
3.9K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
3.9K