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Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies
Baijun Kou1, Wanzhi Huang2, Frederick H Neill1
1Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Journal of Clinical Microbiology
|October 9, 2015
Abstract:
The performance of a norovirus antigen detection assay was assessed using monoclonal antibody NV23 and single-chain antibody HJT-R3-A9 to identify both virus-like particles and virus-containing fecal samples. The detection of 25 different norovirus genotypes as recombinant virus-like particles or in clinical samples was dependent on virus or antigen concentration.
