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Updated: Apr 1, 2026
![Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F55858.jpg&w=3840&q=50)
Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase
Published on: December 4, 2017
Iron-Promoted C-C Bond Formation in the Gas Phase
Anna Troiani1, Marzio Rosi2, Stefania Garzoli3
1Dipartimento di Chimica e Tecnologie del Farmaco, "Sapienza" University of Rome, P.le Aldo Moro 5, 00185 Rome (Italy). anna.troiani@uniroma1.it.
Abstract:
An unusual iron transfer and carbon-carbon coupling take place in gas-phase ionized mixtures containing ferrocene and dichloromethane. Ferrous chloride and the protonated benzenium ion are eventually formed by a thermal and efficient reaction, through stable intermediates that undergo a remarkable reorganization. The mechanism of the concerted iron extrusion, carbon-chlorine bond activation and carbon-carbon bond formation is elucidated by electronic structure calculations that show the crucial role of iron.
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