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Related Concept Videos

Burn Injuries01:22

Burn Injuries

5.0K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
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Predicting mortality in burn patients with bacteraemia.

Alexandra Ceniceros1, Sonia Pértega2, Rita Galeiras3

  • 1Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.

Infection
|October 10, 2015
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Summary

Bacteraemia in burn patients increases mortality risk. Recurrent infections and organ dysfunction, not specific pathogens, are key factors predicting survival in burn patients with bacteraemia.

Keywords:
BacteraemiaBurn patientsMortality

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Area of Science:

  • Medical research
  • Infectious disease
  • Burn care

Background:

  • Bacteraemia negatively impacts burn patient prognosis.
  • Limited analysis of variables influencing clinical progress in these patients.

Purpose of the Study:

  • Identify factors associated with mortality in burn patients experiencing bacteraemia.
  • Analyze clinical and demographic data to understand survival predictors.

Main Methods:

  • Retrospective study of 73 adult burn patients with 103 bacteraemia episodes (2000-2013).
  • Collected demographic, comorbidity, injury, and bacteraemia-related clinical data.
  • Used multiple logistic regression to analyze hospital mortality predictors.

Main Results:

  • Mortality rate was 24.7%.
  • Significant mortality predictors included age (OR=1.13), TBSA (OR=1.05), SOFA score at bacteraemia onset (OR=1.53), and recurrent bacteraemia (OR=41.6).
  • Pseudomonas aeruginosa was the most common pathogen (17.5%).

Conclusions:

  • Recurrent bacteraemia and organ dysfunction (SOFA score) at onset are significant mortality factors.
  • Conventional risk factors like age and TBSA remain important.
  • The specific pathogen identified in bacteraemia episodes was not a prognostic factor for mortality.