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Updated: Apr 1, 2026

Genetic Mapping of Thermotolerance Differences Between Species of Saccharomyces Yeast via Genome-Wide Reciprocal Hemizygosity Analysis
Published on: August 12, 2019
Genetic analysis carried out in population tails reveals diverse two-loci interactions as a basic factor of
Piotr Masojć1, Anna Bienias2, Marcin Berdzik2
1Department of Genetics, Plant Breeding and Biotechnology, West Pomeranian University of Technology in Szczecin, Słowackiego 17, 71-434, Szczecin, Poland. pmasojc@zut.edu.pl.
Abstract:
Bidirectional selective genotyping carried out independently for five quantitative traits within a biparental population of recombinant inbred lines of rye has revealed dramatic changes in alleles distribution in the population tails. A given allele, predominant in the lower tail, is often neutral for reversely directed selection or associates with the upper tail following divergent selection for a related trait. Such radical changes in the alleles distribution cannot be explained by differences in genotypic values within a single locus. This paper presents the theoretical model of a genetic mechanism underlying observed responses of individual loci to divergent selection. The presented model refers to the specific interactions between alleles at two loci. Its wider application in genetic analysis will open up new possibilities for testing positions of genes in the hierarchical structure of interacting loci revealed under selection pressure.
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Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...

