Related Experiment Video
Updated: Apr 1, 2026

10:06
Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
Published on: February 26, 2018
7.9K
Tuberculosis: pH-Responsive Isoniazid-Loaded Nanoparticles Markedly Improve Tuberculosis Treatment in Mice (Small
Angela A Hwang1, Bai-Yu Lee2, Daniel L Clemens2
1Department of Chemistry and Biochemistry, University of California, Los Angeles, 3013 Young Dr. East, CA, 90095-1569, USA.
Small (Weinheim an Der Bergstrasse, Germany)
|October 10, 2015
Abstract:
On page 5066, J. I. Zink, M. A. Horwitz, and co-workers use confocal microscopy to demonstrate the avid uptake of RITC-labeled mesoporous silica nanoparticles loaded with the anti-tuberculosis drug isoniazid (shown here in red) by human macrophages (nuclei stained blue with DAPI) infected with GFP-expressing Mycobacterium tuberculosis (shown here in green).

