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The Spectrum of Psychiatric Pathology in a Patient with Genetically Verified Huntington's Disease

Samir Alkabie1, Daljinder Singh2, Amy Hernandez2

  • 1Department of Psychiatry, Larkin Community Hospital, Miami, FL 33143, USA ; Saba University School of Medicine, Devens, MA 01434, USA.

Case Reports in Psychiatry
|October 10, 2015
PubMed

Insights

Huntington's disease (HD) frequently causes psychiatric issues, impacting patient health and lifespan. This case study illustrates the diverse neuropsychiatric symptoms common in HD, highlighting their significant clinical impact.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Genetics

Background:

  • Psychiatric and behavioral disturbances are prevalent in Huntington's disease (HD).
  • These disturbances significantly contribute to the morbidity and mortality associated with HD.
  • Understanding HD psychopathology is crucial for patient care.

Purpose of the Study:

  • To present a case study of a patient with genetically verified Huntington's disease.
  • To illustrate the spectrum of neuropsychiatric disturbances associated with HD.
  • To review the existing literature on Huntington's disease psychopathology.

Main Methods:

  • Case presentation of a 43-year-old woman with genetically confirmed HD.
  • Detailed description of her deteriorating psychiatric condition and hospitalizations.
  • Literature review on the psychopathology of Huntington's disease.

Main Results:

  • The patient exhibited a wide range of neuropsychiatric disturbances characteristic of HD.
  • Her psychiatric condition required multiple inpatient hospitalizations.
  • The case exemplifies the clinical presentation of HD-related psychopathology.

Conclusions:

  • Psychiatric disturbances are a major clinical feature of Huntington's disease.
  • The presented case underscores the severity and complexity of neuropsychiatric symptoms in HD.
  • Further research and clinical attention to HD psychopathology are warranted.

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