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Updated: Aug 18, 2026

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
Published on: October 25, 2011
Observer variation in histological grading of breast cancer
D S Hopton1, J Thorogood, A D Clayden
1York District Hospital, UK.
Abstract:
A multicentre study was conducted to assess the degree of agreement between pathologists grading breast tumours using the WHO criteria. Satisfactory correlation of grades was found to occur with observer variation of 21.9% on 874 tumours.
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