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Updated: Apr 1, 2026
Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions
Published on: July 22, 2013
Fabrication of electrochemical sensor for paracetamol based on multi-walled carbon nanotubes and chitosan-copper
Airong Mao1, Hongbo Li2, Dangqin Jin3
1School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China; School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China.
Abstract:
An electrochemical sensor for paracetamol based on multi-walled carbon nanotubes and chitosan-copper complex (MWCNTs/CTS-Cu) was fabricated by self-assembly technique. The MWCNTs/CTS-Cu modified GCE showed an excellent electrocatalytic activity for the oxidation of paracetamol, and accelerated electron transfer between the electrode and paracetamol. Under optimal experimental conditions, the differential pulse peak current was linear with the concentration of paracetamol in the range of 0.1-200 μmol L(-1) with a detection limit of 0.024 μmol L(-1). The sensitivity was found to be 0.603 A/mol L(-1). The proposed sensor also showed a high selectivity for paracetamol in the presence of ascorbic acid and dopamine. Moreover, the proposed electrode revealed good reproducibility and stability. The proposed method was successfully applied for the determination of paracetamol in tablet and human serum samples.
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