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Published on: June 8, 2022
Streptococcus pneumoniae necrotizing fasciitis in systemic lupus erythematosus
A Sánchez1, R Robaina1, G Pérez1
1Unidad de Enfermedades Autoinmunes Sistémicas, Clínica Médica "C", Prof. Dr. Juan Alonso Bao, Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Abstract:
Necrotizing fasciitis is a rapidly progressive destructive soft tissue infection with high mortality. Streptococcus pneumoniae as etiologic agent of necrotizing fasciitis is extremely unusual. The increased susceptibility to Streptococcus pneumoniae infection in patients with systemic lupus erythematosus is probably a multifactorial phenomenon. We report a case of a patient, a 36-year-old Caucasian female with 8-year history of systemic lupus erythematosus who presented a fatal Streptococcus pneumoniae necrotizing fasciitis. The role of computed tomography and the high performance of blood cultures for isolation of the causative microorganism are emphasized. Once diagnosis is suspected, empiric antibiotic treatment must be prescribed and prompt surgical exploration is mandatory.
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