Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fabrication of cellulose nanocrystals as potential anticancer drug delivery systems for colorectal cancer treatment.

International journal of biological macromolecules·2022
Same author

Corrigendum to "A dabigatran etexilate phospholipid complex nanoemulsion system for further oral bioavailability by reducing drug-leakage in the gastrointestinal tract" [Nanomedicine: Nanotechnology, Biology, and Medicine 14 (2018) 1455-1464/NANO 1647].

Nanomedicine : nanotechnology, biology, and medicine·2021
Same author

Nano-biotechnology: carbon nanofibres as improved neural and orthopaedic implants.

Nanotechnology·2021
Same author

Ciprofloxacin-Loaded Gold Nanoparticles against Antimicrobial Resistance: An In Vivo Assessment.

Nanomaterials (Basel, Switzerland)·2021
Same author

Improving the self-assembly of bioresponsive nanocarriers by engineering doped nanocarbons: a computational atomistic insight.

Scientific reports·2021
Same author

A Novel Para-Amino Salicylic Acid Magnesium Layered Hydroxide Nanocomposite Anti-Tuberculosis Drug Delivery System with Enhanced in vitro Therapeutic and Anti-Inflammatory Properties.

International journal of nanomedicine·2021
Same journal

Biomimetic Collagen Scaffolds Natural Cross-Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair.

Journal of biomedical materials research. Part A·2026
Same journal

Granular Hydrogel Composites for Noninvasive Optical Biosensing.

Journal of biomedical materials research. Part A·2026
Same journal

Performance Evaluation of Highly Uniform Astragalus Polysaccharide/Silk Fibroin Microspheres Fabricated via Microfluidics as Biodegradable Fillers: Collagen Regeneration and Tissue Reaction.

Journal of biomedical materials research. Part A·2026
Same journal

Combining Supramolecular and Covalent Chemistry to Form Reinforced Fibrillar Network Hydrogels From Fibrinogen Derivatives.

Journal of biomedical materials research. Part A·2026
Same journal

Bioactive-Loaded Detachable Crosslinked Hyaluronic Acid Microneedles: Structural Validation and Clinical Anti-Wrinkle Efficacy.

Journal of biomedical materials research. Part A·2026
Same journal

Tunable Sol-Gel Transition in Poloxamer Blends for Injectable Osteoarticular Applications.

Journal of biomedical materials research. Part A·2026
See all related articles

Related Experiment Video

Updated: Apr 1, 2026

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy
06:00

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy

Published on: May 27, 2022

3.2K

Reducing bone cancer cell functions using selenium nanocomposites.

Michelle Stolzoff1, Thomas J Webster1,2,3

  • 1Bioengineering Department, Northeastern University, Boston, Massachusetts, 02115.

Journal of Biomedical Materials Research. Part A
|October 11, 2015
PubMed
Summary
This summary is machine-generated.

Selenium nanoparticles on poly-L-lactic acid show promise in reducing osteosarcoma recurrence and supporting healthy bone cells. This novel material offers a potential alternative to chemotherapy for bone cancer treatment.

Keywords:
bone regenerationnanocompositesnanomedicineosteosarcomaselenium nanoparticles

More Related Videos

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

6.9K
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.8K

Related Experiment Videos

Last Updated: Apr 1, 2026

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy
06:00

Biological Samples Preparation for Speciation at Cryogenic Temperature using High-Resolution X-Ray Absorption Spectroscopy

Published on: May 27, 2022

3.2K
Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
07:24

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

6.9K
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

7.8K

Area of Science:

  • Biomaterials Science
  • Oncology
  • Nanotechnology

Background:

  • Cancer recurrence post-surgery is a significant threat, especially in aggressive osteosarcoma.
  • Current treatments like chemotherapy have limitations and side effects.
  • Developing novel materials to combat bone cancer recurrence is crucial.

Purpose of the Study:

  • To create a material that inhibits osteosarcoma recurrence.
  • To promote healthy bone cell function.
  • To explore selenium nanoparticles (SeNP) for osteosarcoma applications.

Main Methods:

  • Precipitating selenium nanoparticles (SeNP) onto poly-L-lactic acid (PLLA).
  • Conducting in vitro studies on osteosarcoma cells and osteoblasts.
  • Assessing osteosarcoma cell density and osteoblast function (alkaline phosphatase activity).

Main Results:

  • Selenium-coated PLLA selectively decreased osteosarcoma cell density.
  • Healthy osteoblast functions were promoted, showing increased alkaline phosphatase activity.
  • Effective results were achieved without chemotherapeutics.

Conclusions:

  • Selenium-coated PLLA is a promising material for reducing osteosarcoma recurrence.
  • This approach supports healthy bone tissue regeneration.
  • Further research is warranted for clinical applications in bone tissue engineering.