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Updated: Apr 1, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Recurrent oculomotor neuritis related to autoimmune hypothyroidism. Case Report
Hye-Yeon Choi1, Hak Young Rhee1, Hae-Won Shin2
1Department of Neurology, Kyung Hee University College of Medicine, Kyung Hee University Hospital at Kangdong, Seoul, Republic of Korea.
Abstract:
Ophthalmopathy related to thyroid disease is due mainly to diffuse periorbital or eye muscle inflammation. It is more common in Grave's hyperthyroidism and rare in Hashimoto's hypothyroidism. Here we report a case of recurrent oculomotor nerve palsy associated with autoimmune hypothyroidism. Brain MRI revealed enhancement of the oculomotor nerves. Despite thyroid hormone replacement therapy, oculomotor nerve palsy recurred at the side contralateral to the initially involved nerve and the autoimmune antibody titer remained high. The symptom was responsive to high-dose steroid therapy.
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