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Evaluation of Left Ventricular Function and its Relationship With Multidimensional Grading System (BODE Index) in
Ezgi Kalaycıoğlu1, Tayyar Gökdeniz2, Ahmet Çağrı Aykan1
1a Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital , Department of Cardiology , Trabzon , Turkey.
COPD
|October 13, 2015
Summary
Cardiovascular disease is common in chronic obstructive pulmonary disease (COPD). This study found that a higher BODE index in COPD patients is linked to impaired left ventricle (LV) mechanics, impacting systolic function.
Area of Science:
- Cardiology
- Pulmonology
- Echocardiography
Background:
- Cardiovascular disease (CVD) is a major cause of death in patients with chronic obstructive pulmonary disease (COPD).
- Limited data exists on left ventricle (LV) function in COPD patients.
- The BODE index is a multidimensional prognostic index for COPD.
Purpose of the Study:
- To evaluate left ventricle (LV) systolic function in COPD patients.
- To assess the relationship between LV systolic function and the BODE index in COPD.
- Utilize two-dimensional speckle tracking echocardiography (2D-STE) for LV function assessment.
Main Methods:
- 125 COPD patients and 30 controls underwent 2D-echocardiography, pulmonary function tests, and 6-minute walk tests.
- Patients were stratified into four groups based on BODE index quartiles.
- LV systolic function parameters, including global longitudinal strain (GLS), were analyzed using 2D-STE.
Main Results:
- COPD patients exhibited significantly lower LV systolic function parameters (Sm, GLS, GLSRs, GLSRe, GLSRe, TAPSE, Sm-RV) compared to controls.
- Significant differences in Sm, GLS, and GLSRs were observed across BODE index quartiles.
- The BODE index quartiles were identified as independent predictors of decreased GLS (p = 0.030).
Conclusions:
- Increased BODE index is associated with impaired left ventricle (LV) mechanics in COPD patients.
- 2D-STE is a valuable tool for assessing LV systolic function in COPD.
- Further research is warranted to explore the clinical implications of these findings.
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