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Osteoarthritis in Latin America: Study of Demographic and Clinical Characteristics in 3040 Patients

Anthony M Reginato¹, Humberto Riera, Mariflor Vera

¹From the *Division of Rheumatology, The Warren Alpert School of Medicine, Providence, RI; †Unidad de Reumatología, Instituto Autónomo Hospital Universitario de Los Andes, Universidad de Los Andes; and ‡LabMice, Universidad de Los Andes, Mérida, Venezuela; §Departamento de Reumatología, Instituto Nacional de Rehabilitación, México City; and ∥Departamento de Medicina Interna, Servicio de Reumatologia, Universidad Autonoma de Nuevo León, Mexico; ¶National Coordinator of Rheumatology and the Arthritis Clinical Research Unit at Medicarte, Medellin, Colombia; #Bone and Joint Research Unit, Fundación Jimenez Díaz, Madrid, Spain; **Servicio de Reumatología del Hospital Dr E. Tornu, Buenos Aires, Argentina; ††Catedra de Reumatología de la Facultad de Medicina de la Universidad de la Republica, Montevideo, Uruguay; ‡‡Departamento de Reumatología de la Universidad CES, Medellin, Colombia; §§Departamento de Reumatología, Universidad de Chile; and ∥∥Departamento de Reumatología, Universidad Católica de Chile, Santiago, Chile; ¶¶Servicio de Reumatología del Hospital Quirúrgico 10 de Octubre and ##Servicio de Reumatología del Hospital Frank País, Havana, Cuba; ***Servicio de Reumatología Hospital Santa Cruz, Caja Petrolera de Salud Techo Académico Universidad Católica San Pablo; †††Servicio de Medicina Interna del Hospital Obrero N° 3 de la Caja Nacional de Salud, Santa Cruz, Universidad Santo Tomas De Aquino, Santa Cruz; and ‡‡‡Servicio de Reumatología Kolping y Hospital Alfonzo Gumucio-Techo Académico Universidad Católica San Pablo, San Pablo, Bolivia, §§§Post-Grado de Reumatología, AGAR, FM, UFM, Facultad de Medicina, Universidad Francisco Marroquín, Ciudad de Guatemala, Guatemala; ∥∥∥Servicio de Reumatología, Instituto Salvadoreño del Seguro Social, San Miguel, El Salvador; ¶¶¶Servicio de Reumatología del Hospital de Clínicas de Asunción, Universidad Nacional de Asunción, Asunción, Paraguay; ###

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases

|October 13, 2015

Abstract

Background:

Latin America is a heterogeneous region made up of different populations, cultures, latitudes, altitudes, and immigrants from different areas and ethnic groups.

Objective:

The purpose of this study is to describe the clinical and demographic profile of patients with osteoarthritis (OA) evaluated by a selected group of rheumatologists in 13 Latin American countries.

Methods:

A descriptive, observational, cross-sectional study was conducted in 13 Latin American countries of patients with symptomatic OA. Data were collected over a 3-month period using an ad hoc questionnaire to evaluate the clinical and demographic features of OA seen by rheumatologists.

Results:

Among the 3040 patients, their average age was 62.5 years, and female-to-male ratio was 4.8:1. Patients with body mass index of greater than 30 kg/m or obesity was found in 38.2%. Approximately 88% had primary OA. Joints with OA were as follows: knee 31.2%, hand 9.5%, hand and knee 22.9%, proximal and distal interphalangeal joints (erosive OA) 6.5%, axial 6.6%, and hip 1.3%. Approximately 88.5% had radiographic severity of grade 2 or 3 on Kellgren-Lawrence scale (0-4). Nonsteroidal anti-inflammatory drugs were the predominant OA treatment included in combinations with glucosamine sulfate/chondroitin and viscosupplementation. Associated comorbidities included hypertension (39%), obesity (36.3%), diabetes mellitus (12%), and without comorbidity (12.7%).

Conclusions:

This is 1 of the largest population studies that evaluated the characteristics of OA in 3040 patients evaluated by rheumatologists in 13 Latin American countries. This study provides important data for each Latin American country to develop new health care planning in management of OA.

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