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Updated: Apr 1, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Simultaneous occurrence of sarcomatoid hepatocellular carcinoma and hepatocellular carcinoma
Zhaoqin Huang, Xiangjiao Meng, Qingwei Liu1
1Department of Radiology, Provincial Hospital, Affiliated to Shandong University, Shandong Province, China.
Abstract:
Sarcomatoid hepatocellular carcinoma is a rare disease with a poor prognosis. A 62-year-old man presented with 1-month history of middle-grade fever and fatigue in the background of loss of weight and a history of hepatitis B for 10 years. Dynamic contrast enhanced computed tomography showed two distinct irregular hypodense masses on precontrast scan located in hepatic segment VI and VII with size 6.7×4.7×4.5 cm and 1.9×1.3×1.6 cm. The patient underwent the right hepatectomy. Microscopic examination revealed that the large tumor was sarcomatoid hepatocellular carcinoma and the small tumor was early hepatocellular carcinoma.
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