Primary breast lymphoma with progression to the scalp

Primary lymphomas developing in the breast constitute a rare entity. A 50-year-old female presented with a breast lump for duration of 2 months. She also had a scalp swelling since 2 days. No lymph nodal involvement was present. Histopathological examination and immunohistochemistry performed on a core needle biopsy of the breast lump revealed a diffuse large B-cell non-Hodgkin's lymphoma, an aspirate of the scalp swelling revealed progression from the primary breast lymphoma (PBL). We review the relevant literature and discuss the diagnostic aspects of extranodal lymphomas arising in the breast. Disease progression to the scalp from PBL has not been reported until date. We hereby report the first case of progression to the scalp in a case of PBL.