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Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

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Published on: December 4, 2020

Urethral diverticula in women.

Tamsin J Greenwell¹, Marco Spilotros¹

¹Department of Urology, University College London Hospital, Ground Floor North, 250 Euston Road, London NW1 2PG, UK.

Nature Reviews. Urology

|October 14, 2015

Summary

Female urethral diverticula, though rare, cause urinary incontinence and pain. Vaginal excision offers a highly effective treatment with a low recurrence rate and significant symptom improvement.

Area of Science:

Urology
Gynecology

Background:

Female urethral diverticula are uncommon, benign outpouchings of the urethra.
Symptoms like urinary incontinence, recurrent UTIs, and dyspareunia are often misdiagnosed.
Accurate diagnosis requires clinical examination, MRI, and videocystometrography.

Purpose of the Study:

To review the diagnosis and treatment of female urethral diverticula.
To assess the efficacy and safety of vaginal excision for female urethral diverticula.

Main Methods:

Review of clinical presentation, diagnostic modalities (MRI, videocystometrography), and surgical treatment (vaginal excision).
Evaluation of treatment outcomes, including recurrence rates, symptom resolution, and adverse effects.

Main Results:

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Vessel-sparing Excision and Primary Anastomosis

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Published on: January 7, 2019

Vaginal excision is the preferred treatment with low recurrence and high patient satisfaction.
Significant improvement in dyspareunia, UTIs, and voiding dysfunction post-excision.
50% of patients with pre-existing stress urinary incontinence (USUI) see resolution after surgery.

Conclusions:

Vaginal excision is a safe and effective treatment for female urethral diverticula.
The procedure offers high cure rates for associated symptoms and potential resolution of USUI.
Adverse effects are infrequent and associated with diverticulum complexity and MRI findings.