Related Experiment Video

Updated: Apr 1, 2026

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
07:27

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis

Published on: February 24, 2023

4.0K

Emergence of Melioidosis in Indonesia

Patricia M Tauran, Nurhayana Sennang, Benny Rusli

    The American Journal of Tropical Medicine and Hygiene
    |October 14, 2015
    PubMed

    Insights

    Melioidosis, a serious bacterial infection caused by Burkholderia pseudomallei, is under-recognized in Indonesia. This study highlights three cases in Makassar, emphasizing the need for improved diagnostics and disease awareness.

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Public Health

    Background:

    • Melioidosis is endemic in Southeast Asia and Northern Australia.
    • Cases are infrequently reported in Indonesia, suggesting underdiagnosis.

    Observation:

    • Three cases of melioidosis occurred in Makassar, South Sulawesi, Indonesia, between 2013 and 2014.
    • Two patients died, and one was lost to follow-up.
    • Burkholderia pseudomallei was identified using VITEK2 Compact, but delayed recognition hindered appropriate antimicrobial treatment.

    Findings:

    • A literature review revealed only seven previous reports of melioidosis in Indonesia, with most from before 1960.
    • The study suggests melioidosis is likely endemic throughout Indonesia but remains significantly under-recognized.

    Implications:

    • Enhanced training for accurate and safe identification of Burkholderia pseudomallei is crucial for all microbiological facilities.
    • Consideration should be given to making melioidosis a notifiable disease in Indonesia to improve surveillance and management.

    More Related Videos

    Total Protein Extraction and 2-D Gel Electrophoresis Methods for Burkholderia Species08:31

    Total Protein Extraction and 2-D Gel Electrophoresis Methods for Burkholderia Species

    Published on: October 15, 2013

    30.5K
    The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy12:21

    The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy

    Published on: November 24, 2017

    11.7K

    Related Concept Videos

    Clinical Significance of Antibiotic Resistance01:25

    Clinical Significance of Antibiotic Resistance

    Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
    34
    Investigation of Disease Outbreaks01:23

    Investigation of Disease Outbreaks

    Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
    48
    Infectious Diseases and Their Occurrence01:28

    Infectious Diseases and Their Occurrence

    Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
    54