Related Experiment Video
Updated: Apr 1, 2026

29:13
Microbial Communities in Nature and Laboratory - Interview
Published on: May 28, 2007
6.9K
The proactive historian: Methodological opportunities presented by the new archives documenting genomics
1Science, Technology and Innovation Studies, University of Edinburgh, United Kingdom.
Summary
Historians can navigate genomics archives by actively improving sources, not just relying on time. This approach addresses big data challenges and integrates humanities into global scientific discussions.
Area of Science:
- Genomics and the History of Science
- Scientific Archival Studies
- Big Data Methodologies
Background:
- The study of late-twentieth century genomics faces challenges with newly available archives.
- The 'explosion of data' in genomics is not a novel issue for historical analysis.
- Past historians managed information overload using the 'perspective of time,' a natural filtering process.
Observation:
- Reliance on the 'perspective of time' leads to inheriting pre-curated archives.
- This passive approach risks perpetuating ahistorical scientific narratives.
- Early human genome mapping and sequencing archives exemplify these archival challenges.
Findings:
- Propose a proactive strategy for historians to problematize and enhance archival sources.
- This method empowers historians in managing scientific heritage and advances oral history techniques.
- Suggests focusing on second-order administrators to understand big science initiatives.
Implications:
- Encourages historians to actively engage with 'big data' debates.
- Positions the humanities to contribute to pressing global scientific problems.
- Offers a new framework for analyzing large-scale scientific projects and their socio-political contexts.
Related Concept Videos
Genomics
41.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
41.8K
Next-generation Sequencing
101.1K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
101.1K
Evolutionary Relationships through Genome Comparisons
7.2K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.2K
Modern Molecular Taxonomy
835
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
835
Sanger Sequencing
778.5K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
778.5K
Archival Research
17.6K
Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
17.6K

