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Updated: Apr 1, 2026

Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
Published on: February 23, 2024
Maxillary lateral incisor agenesis and its relationship to overall tooth size
Jane Wright1, Jose A Bosio2, Jang-Ching Chou3
1Adjunct Professor, Department of Developmental Sciences, Marquette University School of Dentistry, Milwaukee, Wis.
Statement Of Problem:
Agenesis of the maxillary lateral incisor has been linked to differences in the size of the remaining teeth. Thus, the mesiodistal space required for definitive esthetic restoration in patients with missing maxillary lateral incisors may be reduced.
Purpose:
The purpose of this study was to determine whether a tooth size discrepancy exists in orthodontic patients with agenesis of one or both maxillary lateral incisors.
Material And Methods:
Forty sets of dental casts from orthodontic patients (19 men and 21 women; mean 15.9 years of age; all of European origin) were collected. All casts had agenesis of one or both maxillary lateral incisors. Teeth were measured with a digital caliper at their greatest mesiodistal width and then compared with those of a control group matched for ethnicity, age, and sex. Four-factor ANOVA with repeated measures of 2 factors was used for statistical analysis (α=.05).
Results:
Orthodontic patients with agenesis of one or both maxillary lateral incisors exhibited smaller than normal tooth size compared with the control group. The maxillary arch had a larger tooth size difference between the control and test groups than the mandibular arch (there was a significant Jaw × Group interaction [F=4.78, P=.032]).
Conclusions:
Agenesis of one or both maxillary lateral incisors is significantly associated with tooth size discrepancy, which may affect the space remaining for restoration of the remaining teeth.
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