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Updated: Apr 1, 2026

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
Published on: October 9, 2018
What is the role of amnioinfusion in modern day obstetrics?
Nimra Dad1, Mandy Abushama2, Justin C Konje3
1a Weill Cornell Medical College Qatar , Ar-Rayyan , Qatar .
Abstract:
Amniotic fluid (AF) is a dynamic medium that plays a significant role in fetal well-being. It is production and amount varies with gestational age. It plays a vital role in fetal life as it contains antimicrobial factors, growth factors and it help the fetal lung to grow and expand. Amnioinfusion can be performed either transabdominally or transvaginal. Amnioinfuion can be done antenatally and during labor. Aminoinfusion can be used for diagnostic purposes to enable better visualization of the fetus as liquor is very important acoustic widow for better fetal examination. Amnioinfusion have some therapeutic benefits in conditions like early premature rupture of membrane and may help cases of external cephalic version for breech presentation at term. Amnioinfusion has been shown to reduce the incidence of variable deceleration due to cord compression, reduces the risk of meconium aspiration and it will help reduce cesarean delivery.
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