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Summary
Dithranol ointment (0.075% and 0.1%) offers a viable treatment option for facial psoriasis vulgaris. Bilateral studies demonstrated its efficacy compared to fluocinolone acetonide cream.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Psoriasis vulgaris is a chronic inflammatory skin condition.
- Facial psoriasis presents unique treatment challenges due to cosmetic and sensitivity concerns.
Purpose of the Study:
- To evaluate dithranol ointment as a topical treatment for facial psoriasis vulgaris.
- To compare the efficacy of dithranol with fluocinolone acetonide in a bilateral study.
Main Methods:
- Bilateral comparison study design.
- Application of dithranol 0.075% and 0.1% L/W cum Spir. Picis lithanthrac. 5% ointment.
- Comparison with fluocinolone acetonide 0.025% (Flucinar cream).
Main Results:
- Dithranol ointment demonstrated effectiveness in treating facial psoriasis.
- The study provides evidence for dithranol as an alternative to corticosteroid treatment.
Conclusions:
- Dithranol ointment is a potential alternative for managing facial psoriasis vulgaris.
- Further research may explore optimal concentrations and long-term outcomes.