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Updated: Apr 1, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
[Epidemiological overview of uterine cervical cancer]
Dulce M Hernández-Hernández1, Teresa Apresa-García, Rosa Ma Patlán-Pérez
1División de Mejora a la Gestión de los Servicios de Salud, Coordinación de Políticas en Salud, Unidad de Educación, Investigación y Políticas de Salud, Instituto Mexicano del Seguro Social, Distrito Federal, México. dulce.hernandez@imss.gob.mx.
Abstract:
The World Health Organization (WHO) reported more than 6 million cases of cancer worldwide in women during 2008; 57.2 % of those cases occurred in less developed countries. Cervical cancer (CC) ranks third in the world in all cancers affecting women, with an estimated of 530 000 new cases. CC has multiple causes and it arises by the association of various risk factors. The main factor is related to the human papillomavirus infection (HPV), which acts as a necessary but not sufficient cause. Also, the interaction with other cofactors has an impact on the development and severity of this neoplasm. Survival is related to the timeliness of care and, therefore, to more access to health services. CC is a neoplasm considered a preventable cancer; thus, it is possible to save more than 150 000 lives by 2030 if control measures are applied with opportunity. The aim of this work is to review the CC in different geographical areas and to make an analysis of risk factors related to this neoplasm.
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