Related Experiment Video
Updated: Mar 31, 2026
12:49
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
3.3K
Living Donor Hepatectomy: Is it Safe?
Anna Weiss1, Viridiana Tapia, Ralitza Parina
1Transplant Division, Department of Surgery, University of California San Diego, San Diego, California, USA.
The American Surgeon
|October 15, 2015
Summary
Living donor hepatectomy (LDH) has significantly lower morbidity and mortality than non-donor hepatectomy. The study suggests LDH
Area of Science:
- Transplantation Surgery
- Organ Donation
- Surgical Outcomes Research
Background:
- Living donor hepatectomy (LDH) carries inherent risks for healthy donors.
- Living donor nephrectomy (LDN) is an established and common procedure.
- A comparative risk assessment of LDH versus LDN is warranted.
Purpose of the Study:
- To evaluate the outcomes of living donor hepatectomy (LDH).
- To compare the risk profile of LDH with living donor nephrectomy (LDN).
Main Methods:
- Utilized the Nationwide Inpatient Sample (NIS) database from 1998 to 2011.
- Identified LDH and LDN cases using donor ICD-9 codes.
- Analyzed in-hospital mortality and complication rates, comparing donors to non-donors and LDH to LDN.
Main Results:
- LDH demonstrated significantly lower in-hospital mortality (0% vs. 6%) and complication rates (4% vs. 33%) compared to nondonor hepatectomy (NDH).
- LDN showed lower mortality (0.8% vs. 1.8%) and complication rates (1% vs. 21%) compared to nondonor nephrectomy (NDN).
- LDH complication rates were higher than LDN (4% vs. 1%), but in-hospital mortality was similar (0% vs. 0.8%).
Conclusions:
- Morbidity and mortality for LDH are substantially lower than for hepatectomy performed for other diseases.
- The risk profile associated with LDH is comparable to that of the widely accepted LDN procedure.
- LDH is a viable option with an acceptable risk profile for living liver donation.
Related Concept Videos
01:28Kidney Transplant I: Introduction
702
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
702
01:26Kidney Transplant II: Surgical Procedure
792
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
792