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Updated: Mar 31, 2026

An Optimized Quantitative Pull-Down Analysis of RNA-Binding Proteins Using Short Biotinylated RNA
Published on: February 17, 2023
A Computational Approach for the Discovery of Protein-RNA Networks
Domenica Marchese1,2, Carmen Maria Livi1,2, Gian Gaetano Tartaglia3,4,5
1Centre for Genomic Regulation (CRG), Dr Aiguader 88, 08003, Barcelona, Spain.
Abstract:
Protein-RNA interactions play important roles in a wide variety of cellular processes, ranging from transcriptional and posttranscriptional regulation of genes to host defense against pathogens. In this chapter we present the computational approach catRAPID to predict protein-RNA interactions and discuss how it could be used to find trends in ribonucleoprotein networks. We envisage that the combination of computational and experimental approaches will be crucial to unravel the role of coding and noncoding RNAs in protein networks.
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