Related Experiment Video
Updated: Mar 31, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Pleuroparenchymal fibroelastosis in association with carcinomas
Eva Baroke1,2, Claus Peter Heussel3,2, Arne Warth2,4
1Department of Pneumology and Respiratory Critical Care Medicine, Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.
Idiopathic pulmonary fibrosis with pleural and lung involvement (PPFE) may be linked to cancer. This study suggests PPFE might have various causes, not just be idiopathic.
Area of Science:
- Pulmonology
- Oncology
- Pathology
Background:
- Pulmonary peliosis and parenchymal fibroelastosis (PPFE) is a rare idiopathic lung disease.
- The etiology of PPFE is not fully understood, with potential contributing factors.
- The association between PPFE and malignancy has not been previously explored.
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