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Updated: Mar 31, 2026
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Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
467
Single- versus multiple-port thoracoscopic lobectomy for lung cancer: a propensity-matched study†
Yaxing Shen1, Hao Wang1, Mingxiang Feng1
1Department of Thoracic Surgery, Zhongshan Hospital of Fudan University, Shanghai, China.
Summary
Single-port (SP) video-assisted thoracoscopic surgery (VATS) offers improved safety and efficacy for non-small-cell lung cancer (NSCLC) resection compared to multiport (MP) VATS. Further research is needed to confirm these benefits.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Minimally Invasive Procedures
Background:
- Non-small-cell lung cancer (NSCLC) is a leading cause of cancer-related mortality.
- Video-assisted thoracoscopic surgery (VATS) has become a standard approach for NSCLC resection.
- Single-port (SP) VATS represents an evolution in minimally invasive thoracic surgery.
Purpose of the Study:
- To compare the safety and efficacy of single-port (SP) versus multiport (MP) VATS for NSCLC lobectomy.
- To evaluate perioperative outcomes between SP and MP VATS in NSCLC patients.
Main Methods:
- Retrospective study of 411 NSCLC patients undergoing VATS lobectomy.
- Propensity-matched analysis comparing SP and MP VATS groups.
- Inclusion of preoperative clinical features for matching.
Main Results:
- SP VATS lobectomy was associated with a shorter operative time for the lobectomy itself (P < 0.001).
- Lymphadenectomy duration was longer in the SP group (P < 0.001).
- No significant differences were observed in total operation duration, blood loss, hospital stay, morbidity, or mortality between SP and MP VATS.
Conclusions:
- SP VATS lobectomy demonstrates comparable safety and efficacy to MP VATS for NSCLC resection.
- SP VATS may offer advantages in specific aspects of the procedure.
- Larger studies are warranted to fully elucidate the benefits of SP VATS for NSCLC.
