Related Experiment Video
Updated: Mar 31, 2026

Author Spotlight: A Pharmacodissection Approach to Uncover Mechanisms in Cardiovascular Disease Risk Populations
Published on: July 21, 2023
Microvascular Complications and Their Associated Risk Factors in Newly Diagnosed Type 2 Diabetes Mellitus Patients
Dipika Bansal1, Kapil Gudala1, Hari Prasad Esam1
1Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Mohali 160062, India.
Abstract:
The study was aimed at assessing the prevalence of microvascular complications and associated risk factors in newly diagnosed type 2 diabetes mellitus patients. A cross-sectional study was conducted in a public tertiary care hospital. All the recruited patients underwent extensive examination for the presence of microvascular complications like neuropathy, retinopathy, and nephropathy. Prevalence of any complication was 18.04%. Prevalence of neuropathy, retinopathy, and nephropathy was found to be 8.2%, 9.5%, and 2.8%, respectively. Triglycerides (OR, 1.01; P = 0.011) and old age (OR, 1.06; P ≤ 0.01) were significantly associated with any complication. Triglycerides were significantly associated with neuropathy (OR, 1.01; P = 0.05) and retinopathy (OR, 1.01; P = 0.02). Being male posed high risk for nephropathy (OR, 0.06; P = 0.01). These results are suggesting need of regular screening for microvascular complications.
Insights
In newly diagnosed type 2 diabetes patients, 18% had microvascular complications. High triglycerides and older age were key risk factors, highlighting the need for regular screening.
Area of Science:
- Endocrinology
- Diabetology
- Public Health
Background:
- Type 2 diabetes mellitus (T2DM) is a growing global health concern.
- Microvascular complications significantly impact patient morbidity and mortality.
- Early identification of risk factors is crucial for effective T2DM management.
Purpose of the Study:
- To determine the prevalence of microvascular complications in newly diagnosed T2DM patients.
- To identify associated risk factors for these complications.
Main Methods:
- A cross-sectional study was conducted in a tertiary care hospital.
- Patients underwent comprehensive examinations for neuropathy, retinopathy, and nephropathy.
- Statistical analysis identified significant risk factors.
Main Results:
- Overall prevalence of any microvascular complication was 18.04%.
- Neuropathy (8.2%), retinopathy (9.5%), and nephropathy (2.8%) were observed.
- Elevated triglycerides and older age were associated with overall complications. Male sex was linked to nephropathy.
Conclusions:
- Newly diagnosed T2DM patients exhibit a notable prevalence of microvascular complications.
- Elevated triglycerides, older age, and male sex are significant risk factors.
- Regular screening for microvascular complications in T2DM patients is recommended.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...

