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Classification of Epithelial Tissues: Overview

Classification of Epithelial Tissues: Overview

Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
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Related Experiment Video

Updated: Mar 31, 2026

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium

Human Colonoid Monolayers to Study Interactions Between Pathogens, Commensals, and Host Intestinal Epithelium

Published on: April 9, 2019

Multicellular density fluctuations in epithelial monolayers.

Steven M Zehnder¹, Marina K Wiatt², Juan M Uruena¹

¹Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida 32611, USA.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics

|October 15, 2015

Summary

This summary is machine-generated.

Cell density fluctuations drive collective cell migration in tissues. Intercellular fluid flow facilitates these density oscillations, revealing a new mechanism for cell-cell interactions in migrating cell groups.

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Last Updated: Mar 31, 2026

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Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation

Quantification of Cellular Densities and Antigenic Properties using Magnetic Levitation

Published on: May 17, 2021

Area of Science:

Cell biology
Biophysics
Tissue dynamics

Background:

Cell size changes and density influence collective cell migration.
Density fluctuations are key in active matter but understudied in cell migration.

Purpose of the Study:

Investigate the role of density fluctuations in collective cell migration.
Analyze spatial and temporal patterns of cell density.
Explore the link between cell density and intercellular fluid flow.

Main Methods:

Studied collective motion in cell monolayers.
Analyzed the divergent component of the migration velocity field.
Used fluorescence measurements of cytosol dye to track fluid movement.

Main Results:

Observed spatial patterns of diverging and converging cell groups.
Found these patterns oscillate with a period of 3-4 hours.
Detected intercellular fluid flow correlating with cell density oscillations.

Conclusions:

Density fluctuations are integral to collective cell migration.
Intercellular fluid flow mediates cell density oscillations.
Cell-cell interactions in monolayers may be regulated by fluid exchange.