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Updated: Mar 31, 2026
A Nanobar-Supported Lipid Bilayer System for the Study of Membrane Curvature Sensing Proteins in vitro
Published on: November 30, 2022
Nanoplasmonic ruler to measure lipid vesicle deformation
Joshua A Jackman1, Barbora Špačková2, Eric Linardy1
1School of Materials Science and Engineering and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Avenue 639798, Singapore. njcho@ntu.edu.sg.
Abstract:
A nanoplasmonic ruler method is presented in order to measure the deformation of adsorbed, nm-scale lipid vesicles on solid supports. It is demonstrated that single adsorbed vesicles undergo greater deformation on silicon oxide over titanium oxide, offering direct experimental evidence to support membrane tension-based theoretical models of supported lipid bilayer formation.
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