Childhood constipation: finally something is moving!

Ilan J N Koppen1,2, Carlo Di Lorenzo2, Miguel Saps2

  • 1a Department of Pediatric Gastroenterology and Nutrition , Emma Children's Hospital/Academic Medical Center , Amsterdam , The Netherlands.

Insights

Recent advancements in pediatric constipation management include new diagnostic tools and treatments. Innovations in colonic and anorectal manometry, electrical stimulation, novel drugs, and surgical approaches are improving outcomes for children with defecation disorders.

Area of Science:

  • Pediatric Gastroenterology
  • Colorectal Surgery
  • Pediatric Urology

Background:

  • Childhood constipation is a prevalent issue impacting children's quality of life.
  • Current management strategies are evolving with new technological and therapeutic advancements.
  • Understanding functional defecation disorders in children requires updated diagnostic approaches.

Purpose of the Study:

  • To provide an update on novel diagnostic and therapeutic tools for childhood constipation.
  • To review recent innovations in colonic and anorectal manometry.
  • To discuss emerging pharmacological, non-pharmacological, and surgical interventions.

Main Methods:

  • Review of recent developments in colonic and anorectal manometry.
  • Analysis of innovative therapies including electrical stimulation and new drug targets.
  • Evaluation of new surgical approaches guided by manometric findings.
  • Assessment of non-pharmacological interventions like fiber and probiotics.

Main Results:

  • Innovations in manometry offer novel insights into pediatric functional defecation disorders.
  • Electrical stimulation and new pharmacological agents show promising therapeutic results.
  • Manometry-guided surgical interventions have improved patient outcomes.
  • Non-pharmacological approaches, including fiber and probiotics, are of significant interest.

Conclusions:

  • Recent advancements are poised to significantly alter the future management of pediatric constipation.
  • A multimodal approach integrating novel diagnostics and therapeutics is crucial for optimal outcomes.
  • Continued research into innovative treatments will further refine the care of children with defecation disorders.

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