Trilateral retinoblastoma with unilateral eye involvement

Area of Science:

• Pediatric Oncology
• Ophthalmology
• Neuro-oncology

Background:

• Retinoblastoma (RB) is the most common primary intraocular tumor in children.
• Trilateral RB (RBT) involves concurrent intraocular and intracranial neuroblastic tumors.
• RBT incidence ranges from 0.5% to 6% in RB patients.

Observation:

• This article presents a case of unilateral RBT.
• The patient was treated at Hospital A.C.Camargo.
• The intracranial neoplasm was of neuroblastic origin.

Findings:

• The case involved a rare combination of unilateral retinoblastoma and a midline intracranial neoplasm.
• The patient received treatment at a specialized cancer hospital.
• This presentation highlights a specific RBT occurrence.

Implications:

• Reporting rare RBT cases aids in understanding its varied presentation.
• Such cases inform diagnostic and treatment strategies for pediatric intraocular and CNS tumors.
• Further research is needed to elucidate RBT pathogenesis and optimize management.