Related Experiment Video
Updated: Mar 31, 2026
07:03
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
Published on: February 15, 2022
1.8K
Sepsis in hemodialysis patients
Gilbert Abou Dagher1, Elie Harmouche2, Elsy Jabbour3
1Department of Emergency Medicine, American University of Beirut, Beirut, Lebanon. ga66@aub.edu.lb.
BMC Emergency Medicine
|October 16, 2015
Summary
Sepsis is a frequent challenge in End Stage Renal Disease (ESRD) patients undergoing hemodialysis (HD). This study found no significant difference in mortality based on Systemic Inflammatory Response Syndrome (SIRS) criteria in this population.
Area of Science:
- Nephrology
- Infectious Diseases
- Critical Care Medicine
Background:
- Bacterial infections and sepsis are common and challenging to diagnose in End Stage Renal Disease (ESRD) patients.
- Hemodialysis (HD) patients present unique diagnostic difficulties for sepsis due to their underlying condition.
Purpose of the Study:
- To analyze sepsis cases in ESRD patients undergoing hemodialysis.
- To investigate the impact of fluid resuscitation, SIRS criteria, and vasopressor use on mortality in this specific patient group.
Main Methods:
- A single-center retrospective study of ESRD patients on HD diagnosed with sepsis, septic shock, or bacteremia.
- Data collected included demographics, infection sources, fluid resuscitation volumes, vasopressor use, and mortality outcomes.
Main Results:
- The most common causes of bacteremia were infections from HD catheters and lower respiratory tract infections.
- Hospital mortality was 26.6%, with 28-day out-of-hospital mortality at 25.6%.
- No significant difference in mortality was observed between patients with fewer than two or two or more SIRS criteria.
Conclusions:
- This study provides an in-depth analysis of sepsis in the dialysis population.
- The findings suggest that SIRS criteria may not be a significant predictor of mortality in ESRD patients with sepsis.
More Related Videos
Related Concept Videos
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
1.6K
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
1.6K
01:24Hemodialysis II: Procedure and Complications
1.8K
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
1.8K
01:25Hemodialysis I: Introduction
3.2K
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
3.2K
01:25Hemodialysis III: Nursing Management
1.5K
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
1.5K
01:27Dialysis
2.0K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
2.0K
01:15Dialysis
2.2K
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
2.2K