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Acute febrile neutrophilic dermatosis
P R Cohen1, L Almeida, R Kurzrock
1College of Physicians and Surgeons of Columbia University, New York, New York.
American Family Physician
|March 1, 1989
Abstract:
Acute febrile neutrophilic dermatosis, or Sweet's syndrome, usually occurs in middle-aged women with a preceding upper respiratory tract infection. In about 20 percent of reported cases, the syndrome is associated with an underlying malignancy, most frequently acute myelogenous leukemia. A dense infiltrate of mature neutrophils is seen in the middle and upper portions of the dermis. Corticosteroid therapy produces rapid improvement of all manifestations of the syndrome.