Related Experiment Video
Updated: Mar 31, 2026
12:31
A Step by Step Protocol for Subretinal Surgery in Rabbits
Published on: September 13, 2016
16.2K
Intraoperative OCT-Assisted Subretinal Perfluorocarbon Liquid Removal in the DISCOVER Study
Ophthalmic Surgery, Lasers & Imaging Retina
|October 16, 2015
Summary
Intraoperative optical coherence tomography (iOCT) guided the removal of subretinal perfluoro-n-octane (PFO). This assistive technique improved surgical maneuvers and led to better visual acuity and retinal anatomy.
Area of Science:
- Ophthalmology
- Surgical Technology
- Medical Imaging
Background:
- Subretinal perfluoro-n-octane (PFO) removal presents surgical challenges.
- Chronic PFO can be loculated and resistant to standard removal techniques.
Observation:
- A prospective study (DISCOVER) evaluated microscope-integrated intraoperative optical coherence tomography (iOCT).
- iOCT was utilized for guidance and feedback during surgical removal of chronic subretinal PFO.
Findings:
- Real-time iOCT feedback successfully guided surgical maneuvers for PFO removal.
- Despite PFO chronicity and resistance, iOCT enabled targeted interventions.
- Postoperative outcomes included improved visual acuity and anatomical normalization.
Implications:
- Microscope-integrated iOCT is a valuable assistive tool in ophthalmic surgery.
- Real-time feedback from iOCT enhances surgical precision during complex procedures.
- This technique shows promise for improving outcomes in challenging subretinal surgeries.
